Abstract Severe acute pancreatitis (SAP) begins with premature activation of enzymes. promoted by the immune system. triggering a potential systemic inflammatory response that leads to organ failure with increased mortality and a bleak prognosis. Interleukin-22 (IL-22) is a cytokine that may have a significant role in SAP. https://ashleyshomestores.shop/product-category/2-piece-outdoor-loveseat-with-cushion/