Background: Irritable bowel syndrome (IBS) is characterized by abdominal pain and altered bowel habits. Further. IBS patients experience a high degree of extraintestinal symptoms. Objectives: The aim of this review was to describe the relation between IBS and extraintestinal manifestations and mechanisms and treatments of these extraintestinal manifestations. https://www.roneverhart.com/Western-Digital-Ultrastar-DC-HC570-WUH722222ALE6L4-0F48155-22TB-7-2K-RPM-SATA-6Gb-s-512e-SE-3-5in-Refurbished-HDD/