In this work we attempt to find out the extent to which realistic prebiotic compartments. such as fatty acid vesicles. would constrain the chemical network dynamics that could have sustained a minimal form of metabolism. We combine experimental and simulation results to establish the conditions under which a reaction network with a catalytically closed organization (more specifically. https://www.roneverhart.com/Western-Digital-Re-WD6001FSYZ-6TB-7-2K-RPM-SATA-6Gb-s-128MB-3-5-Hard-Drive/